Small molecule perimeter defense in entomopathogenic bacteria
نویسندگان
چکیده
منابع مشابه
Small molecule perimeter defense in entomopathogenic bacteria.
Two gram-negative insect pathogens, Xenorhabdus nematophila and Photorhabdus luminescens, produce rhabduscin, an amidoglycosyl- and vinyl-isonitrile-functionalized tyrosine derivative. Heterologous expression of the rhabduscin pathway in Escherichia coli, precursor-directed biosynthesis of rhabduscin analogs, biochemical assays, and visualization using both stimulated Raman scattering and confo...
متن کاملFirebreak: An IP perimeter defense architecture
After many years of research, the Distributed Denial of Service (DDoS) problem remains essentially unsolved, both in industry and in research. Industry solutions rely primarily on beefing up the bandwidth near the attack target, and/or on intercepting traffic at proxies while keeping the target IP address secret. The former approach is expensive, and the latter amounts to “security through obsc...
متن کاملInapproximability of the Perimeter Defense Problem
We model the problem of detecting intruders using a set of infrared beams by the perimeter defense problem: given a polygon P , find a minimum set of edges S of the polygon such that any straight line segment crossing the polygon intersects at least one of the edges in S. We observe that this problem is equivalent to a new hiding problem, the Max-Hidden-Edge-Set problem. We prove the APX-hardne...
متن کاملRegulating Alternative Lifestyles in Entomopathogenic Bacteria
Bacteria belonging to the genera Photorhabdus and Xenorhabdus participate in a trilateral symbiosis in which they enable their nematode hosts to parasitize insect larvae. The bacteria switch from persisting peacefully in a nematode's digestive tract to a lifestyle in which pathways to produce insecticidal toxins, degrading enzymes to digest the insect for consumption, and antibiotics to ward of...
متن کاملEmerging entomopathogenic bacteria for insect pest management
The scientific community working in the field of insect pathology is experiencing an increasing academic and industrial interest in the discovery and development of new bioinsecticides as environmentally friendly pest control tools to be integrated, in combination or rotation, with chemicals in pest management programmes. In this scientific context, market data report a 15% annual growth of the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1201160109